Characteristics of symptomatic reflux episodes in Japanese proton pump inhibitor-refractory non-erosive reflux disease patients

Figure 1 Total liquid reflux episodes and symptoms above the proximal margin of the lower esophagogastric junction at each impedance site. The 325 distal reflux episodes were significantly more frequent (84.9%) than the 58 proximal ones (15.1%) (P < 0.001, distal reflux episodes vs proximal ones). LES: Lower esophagogastric junction.