Protective role of adiponectin in a rat model of intestinal ischemia reperfusion injury

Figure 3 AMPK inhibition attenuated ischemia reperfusion injury. A: Western blot analysis of the expression of p-AMPK and HO-1; B: Western blot analysis of the expression of cleaved caspase 3; C: The serum levels of IL-1β, IL-6, TNF-α, MDA, and SOD and the villus damage score. Compound C: AMPK signaling pathway inhibitor; Snpp, HO-1 inhibitor. Adipo: Adiponectin; Compo. C: Compound C; The data are expressed as mean ± SD obtained from 5 independent experiments. ^aP < 0.05 vs sham, ^bP < 0.05 vs IR, ^cP < 0.05 vs IR + adiponectin. I/R: Ischemia reperfusion; HO-1: Heme oxygenase 1; SOD: Superoxide dismutase; MDA: Malondialdehyde.