Protective role of adiponectin in a rat model of intestinal ischemia reperfusion injury

Figure 2 Adiponectin attenuated ischemia reperfusion injury in rats. A: The expression levels of IL-1β, IL-6, TNF-α, MDA, and SOD, and the villous damage score. The data are expressed as mean ± SD obtained from five independent experiments; B: TUNEL/Hoechst staining was performed to assess the effects of adiponectin treatment on cell apoptosis. Nuclei were stained with Hoechst (blue staining). Apoptotic nuclei were identified by TUNEL staining (green). ^aP < 0.05 vs sham, ^bP < 0.05 vs IR, ^cP < 0.05 vs 0.25 mg/kg group, ^dP < 0.05 vs 0.5 mg/kg group. SOD: Superoxide dismutase; MDA: Malondialdehyde.