Histidine decarboxylase and urinary methylimidazoleacetic acid in gastric neuroendocrine cells and tumours

Table 1 Summary of clinical and tumour characteristics

Tumour type	n	TNM/stage	Age (yr), median (range)	M:F (ratio)	Tumour size (mm)	Localization
Type I ECL cell NETs	37		65 (29-80)	13:24	1-50	Fundus, corpus
	22	T1N0M0/I
	12	T2N0M0/IIa
	2	T2N1M0/IIIb
	1	T2N1M1/IV
Type II ECL cell NETs	3		48 (47-49)	1:2	0.5-25	Fundus, corpus, antrum
	2	T1N0M0/I
	1	T2N1M0/IIa
Type III ECL cell NETs	10		62 (23-77)	4:6	7-55	Fundus, Corpus, antrum
	1	T1N0M0/I
	3	T2N1M0/IIIb
	2	T2N0M1/IV
	2	T2N1M1/IV
	2	T4N1M1/IV
Non-ECL cell NET	1	T2N1M1/IV	71	0:1	20	Corpus, antrum
Ghrelinomas	2	T2N1M1/IV	55 (47-63)	2:0	35-40	Corpus
NECs	11		58 (39-77)	8:3	30-100	Fundus, corpus
Small cell	4
	2	T2N0M0/IIa
	1	T3N1M1/IV
	1	T4N1M1/IV
Large cell	7	T4N0M0/IIIa
	1	T2N1M1/IV
	4	T3N1M1/IV
	1	T4N1M1/IV
	1
Total number	64

TNM/stage according to Rindi et al[23]. ECL cell NETs: Enterochromaffin-like cell neuroendocrine tumours; NECs: Neuroendocrine carcinomas.