HuR mediated post-transcriptional regulation as a new potential adjuvant therapeutic target in chemotherapy for pancreatic cancer

doi:10.3748/wjg.v21.i46.13004

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Dec 14, 2015; 21(46): 13004-13019
Published online Dec 14, 2015. doi: 10.3748/wjg.v21.i46.13004

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Figure 2 HuR, HO-1 and COX-2 mRNA expression analysis in tissues. Quantitative reverse transcription polymerase chain reaction (qRT-PCR) analysis revealed normalized HuR, HO-1, and COX-2 mRNA expression in normal tissues (n = 6) compared to pancreatic cancer tissues (n = 20) with standard deviation (P < 0.05). For normalization, β-actin housekeeping gene and ΔΔCt method was used. HO-1: Heme oxygenase-1; COX-2: Cyclooxygenase-2; HuR: Human antigen R.

Citation: Jakstaite A, Maziukiene A, Silkuniene G, Kmieliute K, Gulbinas A, Dambrauskas Z. HuR mediated post-transcriptional regulation as a new potential adjuvant therapeutic target in chemotherapy for pancreatic cancer. World J Gastroenterol 2015; 21(46): 13004-13019
URL: https://www.wjgnet.com/1007-9327/full/v21/i46/13004.htm
DOI: https://dx.doi.org/10.3748/wjg.v21.i46.13004