Peroxisome proliferator-activated receptor-delta agonist ameliorated inflammasome activation in nonalcoholic fatty liver disease

Figure 1 Effects of high-fat diet for 12 wk on glucose tolerance in male mice treated with GW501516 (GW, 3 mg/kg per day for 3 wk). Intraperitoneal glucose tolerance test (A) and area under the curve for glucose (AUC_glucose) (B) showed glucose intolerance in mice fed the HFD with or without lipopolysaccharide (LPS) injection compared with the control group. GW treatment did not improve glucose intolerance. Data are expressed as the mean ± SD (5-6 mice per group). ^bP < 0.01 vs control group.