Possible association between hepatitis C virus and malignancies different from hepatocellular carcinoma: A systematic review

Table 8 Main findings of studies, concerning the association between hepatitis C virus infection and lymphomas, not considered in the present systematic review because of not reported in English or as full-text or including incomplete data or assessing lymphoproliferative disorders other than B-cell lymphomas

Studies (First author/Journal/Year of publication)	Study title	Main findings for exclusion	Study conclusion
Arcaini L Cancer 2004	Splenic and nodal marginal zone lymphomas are indolent disorders at high hepatitis C virus seroprevalence with distinct presenting features but similar morphologic and phenotypic profiles	Duplicate	High HCV seroprevalence in patients with MZL
Catassi C Rec Prog Med 1998	High prevalence of hepatitis C virus (HCV) infection in patients with non-Hodgkin lymphoma at the onset: preliminary results of a multicentre Italian study	Full-text in Italian	Possible causative role of the HCV in lymphomagenesis
Dal Maso L Haematologica 2004	Hepatitis B and C viruses and Hodgkin lymphoma: a case-control study from northern and southern Italy	Evaluation of the association between HCV infection and HL risk	No role of HCV in the etiology of HL
de Sanjose S Int J Cancer 2004	Role of hepatitis C virus infection in malignant lymphoma in Spain	Duplicate	HCV infection is associated with an increased risk of lymphoma in Spain
Domingo JM Med Clin (Barc) 2001	Hepatitis C virus infection in patients with non Hodgkin's lymphoma	Full-text in Spanish	Possible association between HCV infection and NHLs
Ferri C JAMA 1994	Non-Hodgkin’s lymphoma: possible role of hepatitis C virus	Duplicate	Possible role of HCV infection in B-cell NHLs development
Ferri C QJM 1996	Chronic hepatitis C and B-cell non-Hodgkin's lymphoma	Duplicate	Possible role of HCV infection in B-cell NHLs development
Gasztonyi B Orv Hetil 2000	Hepatitis C virus infection and B-cell non-Hodgkin's lymphoma	Full-text in Humgarian	HCV might have an aetiological role in the lymphoproliferation leading to B-cell NHL
Grudeva-Popova J BUON 2013	Non-Hodgkin lymphomas and carrier state of viral hepatitis B and C	Incomplete data concerning the association between HCV infection and NHLs	Hepatitis virus carrier state did not alter significantly the clinical course and disease prognosis
Izumi T Leukemia 1997	B cell malignancy and hepatitis C virus infection	Duplicate	Association between persistent HCV infection and the occurrence of B- cell malignancy
Montella M Liver 2001	HCV and cancer: a case-control study in a high-endemic area	Duplicate	Expected increases not only in liver cancer, but also in tumors associated with the immune system
Sánchez Ruiz AC Med Clin (Barc) 2001	Prevalence of hepatitis C virus infection in patients with non-Hodgkin's lymphoma	Full-text in Spanish	Higher prevalence of HCV in our B-NHL patients

MZL: Marginal zone lymphoma.