Update on pathogenesis and predictors of response of therapeutic strategies used in inflammatory bowel disease

doi:10.3748/wjg.v21.i44.12519

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Nov 28, 2015 (publication date) through Jan 8, 2025

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Nov 28, 2015; 21(44): 12519-12543
Published online Nov 28, 2015. doi: 10.3748/wjg.v21.i44.12519

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Figure 4 Thiopurines metabolic pathway. XO: Xanthin oxidase; 6-TU: 6-thiouracil; TPMT: Thiopurine methyltransferase; HPRT: Hypoxanthine phosporybosil transferase; 6-MMP: 6-methyl mercaptopurine; 6-TIMP: 6-thiosine 5’ monophosphate; 6-MMPR: 6-methyl mercaptopurine ribonucleotide; IMPD: Inosine monophosphate dehydrogenase; 6-TXMP: 6-Thioxanthosine monophosphate; GMPS: Guanosine monophosphate synthetase; 6-TGN: 6-thioguanine nucleotide; 6-TG: 6-thioguanine; 6-TGDP: 6-thioguanine diphosphate; 6-TGTP: 6-thioguanine triphosphate.

Citation: Quetglas EG, Mujagic Z, Wigge S, Keszthelyi D, Wachten S, Masclee A, Reinisch W. Update on pathogenesis and predictors of response of therapeutic strategies used in inflammatory bowel disease. World J Gastroenterol 2015; 21(44): 12519-12543
URL: https://www.wjgnet.com/1007-9327/full/v21/i44/12519.htm
DOI: https://dx.doi.org/10.3748/wjg.v21.i44.12519