Review
Copyright ©The Author(s) 2015.
World J Gastroenterol. Nov 28, 2015; 21(44): 12558-12575
Published online Nov 28, 2015. doi: 10.3748/wjg.v21.i44.12558
Table 5 Nucleoside analogs in development for hepatitis B virus
NameMOADeveloped byPhase
ClevudineDNA polymerase inhibitionBukwang Pharmaceutical, South KoreaApproved in South Korea and Philippines
BesifovirDNA polymerase inhibition (pro-drug)Ildong Pharmaceuticals and LG Life SciencesPhase III
TenofoviralafenamideDNA polymerase inhibition (pro-drug)Gilead Sciences, United StatesPhase III
CMX157DNA polymerase inhibition (pro-drug)ContraVir Pharmaceuticals, United StatesPhase III
AGX-1009DNA polymerase inhibition (pro-drug)Agenix, AustraliaPhase I