Role of liver transplantation in human immunodeficiency virus positive patients

doi:10.3748/wjg.v21.i43.12311

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Nov 21, 2015; 21(43): 12311-12321
Published online Nov 21, 2015. doi: 10.3748/wjg.v21.i43.12311

Table 1 Drug-drug interactions between directly acting anti-hepatitis C virus directly acting antiviral and combined anti-viral therapy

Anti-HCV DAA	cART not recommended	Dose changes
Boceprevir	Atazanavir
	Darunavir/ritonavir
	Efavirenz
	Ritonavir
Telaprevir	Darunavir	Efavirenz - dose increased
	Lopinavir/ritonavir	to 1125 mg TDS
Simeprevir	Atazanavir
	Efavirenz
	Darunavir/ritonavir
	Nevirapine
Daclatasvir	-	Efavirenz - dose increased to 90 mg OD
		Atazanavir and protease inhibitors - dose reduced to 30 mg OD
Sofosbuvir	Didanosine
	Zidovudine

DAA: Directly acting antiviral; cART: Combined anti-viral therapy; HCV: Hepatitis C virus.

Citation: Joshi D, Agarwal K. Role of liver transplantation in human immunodeficiency virus positive patients. World J Gastroenterol 2015; 21(43): 12311-12321
URL: https://www.wjgnet.com/1007-9327/full/v21/i43/12311.htm
DOI: https://dx.doi.org/10.3748/wjg.v21.i43.12311