MicroRNA in inflammatory bowel disease: Translational research and clinical implication

Table 3 Aberrant microRNA expression in human peripheral blood in ulcerative colitis

Status	Tissue type	Control	Aberrant microRNA expression	Ref.
Active UC	Peripheral blood, n = 13	Healthy	Decreased: miR-505*	Wu et al[31], 2011
			Increased: miR-28-5p, 103-2*,151-5p, 199a-5p, 340*, 362-3p, 532-3p and plus-E1271
	Peripheral blood, n = 88	Healthy	Increased: miR-16, 21, 28-5p, 151-5p, 155 and 199a-5p	Paraskevi et al[32], 2012
Active and inactive UC	Peripheral blood, n = 18	Healthy	Decreased: miR-150 Increased: miR-15b, 19a, 24, 27a, 28-3p, 29a, 30e, 93, 103, 128, 142-5p, 196b, 199a-3p, 221, 223, 345, 374b, 423-5P, 532-5p, 598, 760, let-7d, let-7e and let-7g	Iborra et al[25], 2013
Inactive UC	Peripheral blood, n = 13	Healthy	Decreased: miR-505*	Zahm et al[33], 2011
			Increased: miR-103-2, 362-3p and 532-3p
Inactive UC	Peripheral blood, n = 10	Healthy	Decreased: miR-505*	Wu et al[31], 2011
			Increased: miR-103-2*, 362-3p and 532-3p
Unknown	Peripheral blood, n = 20	Healthy	Increased: miR-20b*, 22, 27a*, 31, 92a-1*, 138, 140-3p, 143*, 146a-3p, 150*,181b, 188-5p, 330-3p, 362-5p, 345, 378, 378*,422a, 500, 501-5p, 532-5p, 550*, 720, 769-3p, 769-5p, 874, 941, 1271, 1274b, 1296 and let-7i*	Duttagupta et al[34], 2012
	Peripheral blood, n = 15	Healthy	Increased: miR-21	Yang et al[24], 2013

UC: Ulcerative colitis.