Hepatocellular carcinoma in the elderly: Meta-analysis and systematic literature review

Table 4 Preoperative data of patients with hepatocellular carcinoma who underwent radiofrequency ablation

Author	Year	Country	Design	Treatment	Age cut off	Young, n	Elderly, n	Sex: male/female (P = 0.031)		Child Pugh A/B/C		Tumor size (cm) (P = 0.662)
								Young	Elderly	Young	Elderly	Young	Elderly
Takahashi et al[24]	2010	Japan	Prospective	RFA	75	354	107	218/136	46/61	278/76	77/30	NA	NA
Mirici-Cappa et al[13]	2010	Italy	Retrospective	RFA or PEI	70	230	195	165/65	118/77	147/70/10	157/33/2	3.04	3.13
Nishikawa et al[25]	2012	Japan	Prospective	RFA	75	238	130	150/88	67/63	145/36/4	87/16	1.92	2.31
Liu et al[20]	2014	Taiwan	Prospective	RFA	75	336	147	221/115	96/51	80/17/3	89/11	NA	NA
Fujiwara et al[26]	2014	Japan	Retrospective	RFA	75	1048	353	705/343	191/162	782/255/11	287/63/3	2.40	2.50

RFA: Radiofrequency ablation; NA: Not available.