Hepatocellular carcinoma in the elderly: Meta-analysis and systematic literature review

Table 3 Co-morbidities of patients with hepatocellular carcinoma who underwent surgical resection

Author	Year	Country	CV co-morbidities (P = 0.341)		Resp co-morbidities (P = 0.031)		Diabetes (P = 0.086)		Alcohol (P = 0.737)
			Young	Elderly	Young	Elderly	Young	Elderly	Young	Elderly
Yau et al[27]	1999	China	NA	NA	NA	NA	NA	NA	NA	NA
Chen et al[7]	1999	Taiwan	47.60%	12.60%	8.40%	14.30%	5.40%	14.30%	NA	NA
Hanazaki et al[8]	2001	Japan	11.00%	24.30%	7.40%	19.40%	8.50%	31.10%	NA	NA
Yeh et al[9]	2004	Taiwan	NA	NA	NA	NA	15.30%	38.20%	NA	NA
Ferrero et al[10]	2005	Italy	NA	NA	NA	NA	NA	NA	31.10%	20.30%
Kaibori et al[11]	2009	Japan	16%	39%	4%	16%	7%	23.00%	48.30%	35.40%
Oishi et al[4]	2009	Japan	NA	NA	NA	NA	NA	NA	NA	NA
Huang et al[12]	2009	China	NA	NA	NA	NA	NA	NA	NA	NA
Mirici-Cappa et al[13]	2009	Italy	NA	NA	NA	NA	NA	NA	12.90%	21.40%
Tsujita et al[14]	2012	Japan	11.90%	22.00%	13.00%	8.70%	29.40%	21.70%	NA	NA
Yamada et al[15]	2012	Japan	NA	NA	NA	NA	NA	NA	NA	NA
Nishikawa et al[16]	2013	Japan	13.10%	50.80%	10.70%	15.20%	33.50%	26.00%	NA	NA
Hirokawa et al[17]	2013	Japan	NA	NA	NA	NA	NA	NA	NA	NA
Ide et al[18]	2013	Japan	NA	NA	NA	NA	NA	NA	NA	NA
Taniai et al[19]	2013	Japan	NA	NA	NA	NA	NA	NA	NA	NA
Liu et al[20]	2014	Taiwan	NA	NA	NA	NA	NA	NA	15.00%	10.00%
Kishida et al[21]	2015	Japan	NA	NA	NA	NA	NA	NA	16.00%	18.00%
Kim et al[22]	2015	South Korea	NA	NA	NA	NA	13.70%	25.00%	3.20%	5.10%

NA: Not available.