Pathophysiological mechanisms of death resistance in colorectal carcinoma

doi:10.3748/wjg.v21.i41.11777

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Nov 7, 2015 (publication date) through Nov 15, 2024

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Nov 7, 2015; 21(41): 11777-11792
Published online Nov 7, 2015. doi: 10.3748/wjg.v21.i41.11777

Table 1 Alteration of apoptotic and necroptotic regulators in human colon cancers

Classification	Molecule	Expression in cancer tissues	Ref.
Bcl-2 family	Bcl-X_L	Increased	[56]
IAP family	cFLIP	Increased	[57]
	cIAP2	Increased	[59,60]
	survivin	Increased	[55,61]
	XIAP	Increased	[58]
RIP kinase family	RIPK1/RIPK3	Decreased	[62]

IAP: Inhibitor of apoptosis protein; FLIP: FLICE-like inhibitory protein; XIAP: X-linked IAP; RIP: Receptor-interacting protein.

Citation: Huang CY, Yu LCH. Pathophysiological mechanisms of death resistance in colorectal carcinoma. World J Gastroenterol 2015; 21(41): 11777-11792
URL: https://www.wjgnet.com/1007-9327/full/v21/i41/11777.htm
DOI: https://dx.doi.org/10.3748/wjg.v21.i41.11777