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Copyright ©The Author(s) 2015.
World J Gastroenterol. Nov 7, 2015; 21(41): 11709-11739
Published online Nov 7, 2015. doi: 10.3748/wjg.v21.i41.11709
Table 4 Diagnostic and prognostic cellular long non-coding RNAs in colorectal cancer
Clinical featureOncogenesTumor suppressor genesPMID
Disease-free survivalAK026784, AK024680, MALAT1AK123657, CR622106, BX649059, BX648207, TUSC7, RPL34-AS124809982, 25031737, 23680400, 24908062
Distant metastasis91H, PCAT1, CCAT1TUSC7, RPL34-AS125058480, 23640607, 23594791, 23680400, 24908062
Liver metastasisHOTAIR, HULCncRAN21862635, 24519959, 19445043
Lymph node metastasisPVT-1, AK021444, ENST00000425785, AK307796ENST0000046584624196785, 25009386
Metastasis riskMALAT125031737
Overall survivalMALAT1, PVT-1, PCAT1ncRAN, uc.7325031737, 24196785, 24519959, 23640607, 22328099
Plasma diagnostic markerCRNDE22393467
Poor prognosisHOTAIR, 91H, PVT-121862635, 25058480, 24196785
Tumour riskPRNCR1 (SNP)24330491
Tumour sizeHOTAIR, PRNCR1 (SNP)TUSC721862635, 23680400, 24330491
Tumour stageCCAT1lincRNA-p21, TUSC7, RPL34-AS124012455, 23594791, 23680400, 24908062
Undifferentiated phenotypeHOTAIR, PRNCR1 (SNP)ncRAN21862635, 24519959, 24330491
Venous invasionPVT-1lincRNA-p2124196785, 24012455