Copyright
©The Author(s) 2015.
World J Gastroenterol. Nov 7, 2015; 21(41): 11552-11566
Published online Nov 7, 2015. doi: 10.3748/wjg.v21.i41.11552
Published online Nov 7, 2015. doi: 10.3748/wjg.v21.i41.11552
Table 3 Genetic polymorphisms associated with the outcomes of hepatitis B virus infection
Gene | Risk allele | Association | Population | Ref. |
Immune response mediators | ||||
IL-10 | -592 C | Significant increased risk of LC | Asian | [139] |
IL-28B | rs12979860 C | Increased risk for developing LC | Asian | [140] |
TGF-β1 | 10 T | Higher prevalence of LC | Chinese | [141] |
TGF-β1 | -509 C | Higher susceptibility to LC | Chinese | [142] |
Fibrogenesis | ||||
COL1A1 | TC haplotype (-1997 T, -1363 C) | Higher prevalence of LC | Chinese | [143] |
COL3A1 | rs3106796 A | Higher prevalence of chronic hepatitis, LC and HCC | Koreans | [144] |
- Citation: Ramos-Lopez O, Martinez-Lopez E, Roman S, Fierro NA, Panduro A. Genetic, metabolic and environmental factors involved in the development of liver cirrhosis in Mexico. World J Gastroenterol 2015; 21(41): 11552-11566
- URL: https://www.wjgnet.com/1007-9327/full/v21/i41/11552.htm
- DOI: https://dx.doi.org/10.3748/wjg.v21.i41.11552