Copyright
©The Author(s) 2015.
World J Gastroenterol. Oct 28, 2015; 21(40): 11282-11303
Published online Oct 28, 2015. doi: 10.3748/wjg.v21.i40.11282
Published online Oct 28, 2015. doi: 10.3748/wjg.v21.i40.11282
Figure 1 Metabolism of azatioprine and 6-mercaptopurine.
AZA: Azathioprine; 6-MP: 6-mercaptopurine; 6-MeMP: 6-methylmercaptopurine; 6-TU: 6-thiouric acid; 8-OH 6MP: 8-hydroxymercaptopurine; 6Me-tIMP: 6-methyl thioinosine monophosphate; 6-tIMP: 6-thioinosine monophosphate; 6-TIDP: 6-thioinosine diphosphate; 6-TITP: 6-thioinosine triphosphate; 6-MeTITP: 6-methylthioinosine triphosphate; tXMP: Thioxanthine monophosphate tGMP: Thioguanine monophosphate; tGDP: Thioguanine diphosphate; tGTP: Thioguanine triphosphate; Me-tGMP: Methylthioguanine monophosphate; Deoxy-tGTP: Deoxythioguanine triphosphate; GST: Glutathione S-transferasa; TPMT: Thipurine methyltransferase; XDH: Xanthine dehydrogenase; AO: Aldehyde oxidase; HGPRT: Hypoxanthine guanine phosphoribosyltransferase; IMPDH: Inopine monophosphate dehydrogenase; GMPS: Guanosine monophosphate synthetase; PK: Phosphokinase; rPK: Reductase phosphokinase.
- Citation: Gómez-Gómez GJ, Masedo &, Yela C, Martínez-Montiel MDP, Casís B. Current stage in inflammatory bowel disease: What is next? World J Gastroenterol 2015; 21(40): 11282-11303
- URL: https://www.wjgnet.com/1007-9327/full/v21/i40/11282.htm
- DOI: https://dx.doi.org/10.3748/wjg.v21.i40.11282