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Copyright ©The Author(s) 2015.
World J Gastroenterol. Oct 28, 2015; 21(40): 11282-11303
Published online Oct 28, 2015. doi: 10.3748/wjg.v21.i40.11282
Table 6 Treatment algorithm according to antidrug antibodies and drug levels
Anti-TNF-αdrug levelsAntibodiesAction
LowNegativeIncrease dose
LowPositiveSwitch drug
HighNot determinedSwitch to a drug with a different mechanism of action