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Copyright ©The Author(s) 2015.
World J Gastroenterol. Oct 28, 2015; 21(40): 11282-11303
Published online Oct 28, 2015. doi: 10.3748/wjg.v21.i40.11282
Table 5 Risk factors associated to secondary failure or loss of response
Individual differences in bioavailability and pharmacokinetics
Symptoms not due to inflammatory bowel disease
Lack of adherence to therapy
Drug loss in stools
Intermittent treatments
Non-inflammatory symptoms
Structuring disease pattern
Smoking
Development of antibodies