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Copyright ©The Author(s) 2015.
World J Gastroenterol. Oct 28, 2015; 21(40): 11282-11303
Published online Oct 28, 2015. doi: 10.3748/wjg.v21.i40.11282
Table 1 Azatioprine treatment basis of individual thiopurine methyltransferase status
TMPT genotypeTPMT fenotype (pmol/mgHb)Treatment dosis(mg/kg)
Homozygous< 10Avoid or consider 0.1-0.2
Heterozygous10-241-1.5
Wild type (normal)25-352-2.5
Wild type (high)> 350.5 + 100 mg allopurinol