Disease monitoring in inflammatory bowel disease

Table 4 Fecal calprotectin values and correlating endoscopic scores

Ref.	Disease	Endoscopic tool	Endoscopic score (descriptor)	Calculation	Calprotectin scores
Falvey et al[71]	CD	SES-CD	0-2 (inactive)	mean (95%CI)	55 μg/g (25-123)
			3-6 (mild)		167 μg/g (97-288)
			7-15 (moderate)		366 μg/g (192-698)
			16+ (severe)		732 μg/g (338-1587)
Sipponen et al[49]	CD	SES-CD	≤ 3 (inactive-mild)	Median (range)	37 μg/g (13-166)
			> 3 (active)		686 μg/g (18-15326)
Sipponen et al[62]	CD	CDEIS	< 3 (inactive)	Median (range)	63 μg/g (11-869)
			3-9 (mild)		170 μg/g (17-2440)
			9-12 (moderate)		1014 μg/g (123-2284)
			> 12 (severe)		2066 μg/g (323-18575)
Schoepfer et al[77]	CD	SES-CD	0-3 (inactive)	mean (range)	104 μg/g (10-725)
			4-10 (mild)		231 μg/g (12-1009)
			11-19 (moderate)		395 μg/g (68-912)
			≥ 20 (high)		718 μg/g (93-1327)
Lobatón et al[48]	CD	CDEIS	< 3 (endoscopic remission)	Median (range)	101.8 μg/g (30-1620.9)
			≥ 3 (endoscopic activity)		1211.9 μg/g (122-1800)

CDEIS: Crohn’s disease endoscopic index of severity; SES-CD: Simple endoscopic score for Crohn’s disease.