Weichang’an and 5-fluorouracil suppresses colorectal cancer in a mouse model

Figure 5 Western blot analysis of β-catenin and matrix metalloproteinase-7 protein expression in orthotopic and hepatic metastatic tumors. A, B: Quantification of β-catenin and matrix metalloproteinase (MMP)-7 expression in orthotopic tumors (A) and hepatic metastatic tumors (B). Data were presented as mean ± SD and ^aP < 0.05 vs corresponding CON group; C: β-catenin expression in orthotopic tumors; D: MMP-7 expression in orthotopic tumors; E: β-catenin expression in hepatic metastatic tumors; F: MMP-7 expression in hepatic metastatic tumors. Lanes 1-3, CON group; 4-6, WCA group; 7-9, 5-FU group; and 10-12, WCA + 5-FU group. WCA: Weichang’an; 5-FU: 5-fluorouracil; CON: Control.