Hyperhomocysteinemia as a potential contributor of colorectal cancer development in inflammatory bowel diseases: A review

Figure 1 Metabolism of homocysteine[7]. dUMP: Desoxyuridine monophosphate; dTMP: Desoxytimidine monophosphste; THF: Tetrahydrofolate; DHF: Dihydrofolate; 5-MTHF: 5-methyltetrahydrofolate; 5,10-MTHF: 5,10-methyltetrahydrofolate; 5,10 MTHFR: 5,10- methyltetrahydrofolate reductase; MS: Metionin synthase; MSR: Metionin synthase reductase; B12: Vitamin B12; SAM: S-adenosylmethionine; SAH: S-adenosylhomocysteine; CBS: Cystathionine β-synthase; GCT: γ-cystathionase; B6: Vitamin B6.