Preoperative CA 125 is significant indicator of curative resection in gastric cancer patients

Table 2 Univariate and multivariate analysis of the risk factors for a non-curative operations n (%)

Variables	Univariate analysis			Multivariate analysis
	Curative	Non-curative	P value	HR (95%CI)	P value
Age, yr			0.189		0.238
< 60	272 (95.1)	14 (4.9)
≥ 60	364 (92.6)	29 (7.4)		1.599 (0.733-3.487)
Sex			0.574		0.642
Male	417 (93.3)	30 (6.7)
Female	219 (94.4)	13 (5.6)		0.832 (0.384-1.803)
Differentiation			0.080		0.082
Differentiated	382 (95.0)	20 (5.0)
Undifferentiated	254 (91.7)	23 (8.3)		1.937 (0.919-4.085)
Location			< 0.001		< 0.001
Lower 1/3	359 (93.2)	26 (6.8)
Middle 1/3	212 (97.2)	6 (2.8)		0.334 (0.120-0.928)	0.036
Upper 1/3	60 (90.9)	6 (9.1)		1.223 (0.421-3.555)	0.711
Whole	5 (50.0)	5 (50.0)		21.303 (4.985-91.036)	< 0.001
CEA			0.038
Negative	579 (94.3)	35 (5.7)			0.792
Positive	57 (87.7)	8 (12.3)		1.142 (0.427-3.056)
CA 19-9			< 0.001		< 0.001
Negative	586 (95.6)	27 (4.4)
Positive	50 (75.8)	16 (24.2)		5.883 (2.569-13.474)
CA 125			< 0.001		< 0.001
Negative	616 (95.7)	28 (4.3)
Positive	20 (57.1)	15 (42.9)		15.549 (6.473-37.352)

CEA: Carcinoembryonic antigen; CA: Carbohydrate antigen.