Serum vitamin D3 does not correlate with liver fibrosis in chronic hepatitis C

Table 3 Correlations of serum 25(OH)D₃ and 24,25(OH)₂D₃ levels, and the 25(OH)D₃/24, 25(OH)₂D₃ ratio, with clinical parameters

	25(OH)D3 (ng/mL)		24,25(OH)2D3 (ng/mL)		25(OH)D3/24,25(OH)2D3
	r value	P value	r value	P value	r value	P value
Age (yr)	-0.034	0.711	-0.132	0.150	-0.134	0.145
ALT (U/L)	-0.062	0.502	0.175	0.055	-0.230	0.012
AST (U/L)	0.036	0.693	0.169	0.066	-0.149	0.104
TBIL (μmol/L)	-0.124	0.177	0.088	0.337	-0.176	0.054
DBIL (μmol/L)	-0.165	0.072	0.109	0.065	-0.282	0.002
TP (g/L)	-0.126	0.170	0.136	0.138	-0.185	0.043
ALB (g/L)	0.027	0.770	0.120	0.193	-0.112	0.223
GGT (U/L)	-0.143	0.119	0.104	0.260	-0.211	0.021
CHE (U/L)	-0.015	0.871	-0.058	0.526	-0.011	0.906
Ca (mmol/L)	0.027	0.768	0.200	0.028	-0.158	0.084
P (mmol/L)	0.088	0.337	-0.130	0.158	0.266	0.003
HB (g/L)	-0.040	0.665	0.133	0.149	-0.195	0.033
PTA (%)	0.109	0.237	-0.134	0.145	0.231	0.011
Liver fibrosis	-0.052	0.574	0.023	0.807	-0.072	0.435
Liver inflammation	-0.104	0.258	-0.129	0.160	0.069	0.451
Viral load( IU/mL)	0.074	0.464	0.173	0.086	-0.131	0.196
25(OH)D3 (ng/mL)	-	-	0.410	< 0.001	-	-
24,25(OH)2D3 (ng/mL)	0.410	< 0.001	-	-	-	-

ALT: Alanine aminotransferase; AST: Aspartate aminotransferase; TBIL: Total bilirubin; DBIL: Direct bilirubin; TP: Total protein; ALB: Albumin; GGT: Gamma-glutamyl transpeptidase; CHE: Cholinesterase; HB: Hemoglobin; PLT: Platelets; PTA: Prothrombin time activity.