Clinical significance of donor-specific human leukocyte antigen antibodies in liver transplantation

Table 1 Association of graft fibrosis and concomitant anti-human leukocyte antigen class II donor-specific anti-human leukocyte antigen antibodies

Ref.	No. of patients	Positive for HLA Abs	Transplant type	Follow-up. median (yr)	Time detection DSA	Method detection DSA	MFI
Miyagawa-Hayashino et al[78]	79	32	LD	11	After LT	SAB	> 5000
Salah et al[58]	114	5	LD	2	After LT	SAB	> 5000
O´Leary et al[60]	507	46	DD	6.4	Pre and after LT	SAB	> 5000
Grabhorn et al[72]	19	16	LD + DD	4.5	After LT	SAB	> 5000
Iacob et al[79]	174	34	LD + DD	ND	After LT	SAB	> 5000

HLA: Human leukocyte antigen; DSA: Donor-specific anti-HLA antibodies; SAB: Single-antigen-bead; MFI: Mean fluorescence intensity; LT: Liver transplant.