Dimethyl sulfoxide inhibits zymosan-induced intestinal inflammation and barrier dysfunction

Figure 8 Intestinal ZO-1 immunofluorescent staining at 4 h, 8 h, and 24 h after injection of zymosan. Animals in group ZS showed low fluorescent intensity at the cell periphery after intraperitoneal injection of zymosan, and DMSO administration resulted in preservation of ZO-1 staining. All images were taken at × 400 magnification with the black bar = 5 μm (n = 5 per group). DMSO: Dimethyl sulfoxide; SS: Sham with administration of normal saline; SD: Sham with administration of DMSO; ZS: Zymosan with administration of normal saline; ZD: Zymosan with administration of DMSO.