Risk factors for adverse in-hospital outcomes in acute colonic diverticular hemorrhage

Table 3 Risk factors for transfusion need within 24 h of admission (n = 153)

	None/transfusion within 24 h (n = 119/34)	Crude OR(95%CI)	P value	Adjusted OR1(95%CI)	P value
Age > 70 yr	58 (49)/24 (71)	2.5 (1.1-5.7)	0.03
Female	34 (29)/17 (50)	2.5 (1.1-5.5)	0.02	2.7 (1.2-6.2)	0.02
Current smoker	28 (24)/13 (38)	2.0 (0.89-4.5)	0.09
Current drinker	80 (67)/28 (82)	2.3 (0.87-5.9)	0.09
NSAIDs	32 (27)/9 (26)	0.98 (0.41-2.3)	0.96
Low-dose aspirin	24 (20)/14 (41)	2.8 (1.2-6.3)	0.01
Non-aspirin antiplatelets	20 (17)/9 (26)	1.8 (0.72-4.4)	0.21
Warfarin	4 (3.4)/6 (18)	6.2 (1.6-23)	< 0.01	4.6 (1.8-29)	< 0.01
Acetaminophen	2 (1.7)/0	1.5 (0-19)2	1.0
Corticosteroids	5 (4.2)/0	0.51 (0-3.8)2	0.56
Hypertension	73 (61)/25 (74)	1.8 (0.75-4.1)	0.20
Diabetes mellitus	25 (21)/6 (18)	0.81 (0.30-2.2)	0.67
Dyslipidemia	25 (21)/7 (21)	0.97 (0.38-2.5)	0.96
Cerebro-cardiovascular disease	25 (21)/15 (44)	3.0 (1.3-6.7)	< 0.01
Chronic liver disease	6 (5.0)/0	0.41 (0-3.0)2	0.43
Chronic kidney disease	7 (5.9)/6 (18)	3.4 (1.1-11)	0.04	3.6 (1.0-12)	0.04

¹Multiple logistic regression analysis, using the backward elimination method, of factors found to be significant (P < 0.05) on univariate analysis;

²Analysis by exact logistic regression. NSAIDs: Non-steroidal anti-inflammatory drugs.