Copyright
©The Author(s) 2015.
World J Gastroenterol. Oct 7, 2015; 21(37): 10654-10661
Published online Oct 7, 2015. doi: 10.3748/wjg.v21.i37.10654
Published online Oct 7, 2015. doi: 10.3748/wjg.v21.i37.10654
Table 2 Characteristics of histological and endoscopic features in ulcerative colitis patients before and after induction therapy with infliximab
| Parameter | Week 0 | Week 8 |
| Histopathological features | ||
| Grade > 3 | 4/16 | 1/16 |
| Grade 3 | 10/16 | 8/16 |
| Grade 2 | 2/16 | 2/16 |
| Grade 1 | 0/16 | 2/16 |
| Grade 0 | 0/16 | 3/16 |
| Irregular surface | 12/16 | 6/16 |
| Abnormal crypt architecture | 9/16 | 8/16 |
| Reduced number of the crypts | 10/16 | 7/16 |
| Cryptitis | 11/16 | 6/16 |
| Epithelial changes | 8/16 | 6/16 |
| Mucin depletion | 6/16 | 6/16 |
| Increased intraepithelial lymphocytes | 3/16 | 5/16 |
| Baron scale, mean ± SD | 2.5 ± 0.6325 | 1.5 ± 0.9661 (P = 0.0033) |
| Baron 0 | 0/16 | 2/16 |
| Baron 1 | 1/16 | 7/16 |
| Baron 2 | 6/6 | 4/16 |
| Baron 3 | 9/16 | 3/16 |
- Citation: Wiernicka A, Szymanska S, Cielecka-Kuszyk J, Dadalski M, Kierkus J. Histological healing after infliximab induction therapy in children with ulcerative colitis. World J Gastroenterol 2015; 21(37): 10654-10661
- URL: https://www.wjgnet.com/1007-9327/full/v21/i37/10654.htm
- DOI: https://dx.doi.org/10.3748/wjg.v21.i37.10654