Histological healing after infliximab induction therapy in children with ulcerative colitis

Table 1 Characteristics of clinical and biochemical parameters before and after induction therapy with infliximab

Parameter	Week 0				Week 8				P value
	mean	Median	Q1	Q3	mean	Median	Q1	Q3
PUCAI score	49.1	50	35	65	16.3	10	10	20	< 0.05
Body weight (kg)	46.5	44	43	56.6	50.4	53.3	42.7	60.5	< 0.05
Body height (cm)	157.3	163	151	168.5	158.2	163.5	152	170	NS
Hemoglobin (g/dL)	9.9	9.8	8.3	11.3	11	11	10	12.2	< 0.05
Hematocrit (%)	35.8	31.5	29.2	35.8	33.9	34.9	30.1	37.2	NS
Platelet count (K/μL)	441.1	427	327.5	558	384	375.5	290	440.5	NS
ESR (mm/h)	33	36	18.5	45	19.8	12.5	7	22.5	< 0.05
CRP (mg/dL)	2.6	2.8	0.4	4.1	0.3	0.2	0	0.4	< 0.05

Q1: Lower quartile; Q3: Upper quartile; NS: Not significant.