Biomarkers for the early diagnosis of hepatocellular carcinoma

doi:10.3748/wjg.v21.i37.10573

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Oct 7, 2015 (publication date) through Mar 7, 2025

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World Journal of Gastroenterology

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1007-9327

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World J Gastroenterol. Oct 7, 2015; 21(37): 10573-10583
Published online Oct 7, 2015. doi: 10.3748/wjg.v21.i37.10573

Table 2 Early diagnostic values of hepatocellular carcinoma serum biomarkers

Biomarker	Sensitivity, % (95%CI)	Specificity, % (95%CI)	Ref.
AFP	53 (46-59)	90 (87-93)	[17]
AFP-L3	28 (22-34)	97 (93-100)	[17]
DCP	61 (55-68)	70 (65-74)	[17]
GPC3	55.1 (47.9-66.2)	97.0 (95.2-98.2)	[42]
OPN	75 (58-93)	62 (51-73)	[50]
GP73	62	88	[56]
miRNA panel¹	82.5	83.5	[101]

¹Including miR-122, miR-192, miR-21, miR-223, miR-26a, miR-27a and miR-801.

Citation: Tsuchiya N, Sawada Y, Endo I, Saito K, Uemura Y, Nakatsura T. Biomarkers for the early diagnosis of hepatocellular carcinoma. World J Gastroenterol 2015; 21(37): 10573-10583
URL: https://www.wjgnet.com/1007-9327/full/v21/i37/10573.htm
DOI: https://dx.doi.org/10.3748/wjg.v21.i37.10573