Endoscopic surveillance of gastric cancers after Helicobacter pylori eradication

Table 2 Incidence of multiple gastric cancers after endoscopic resection of primary early gastric cancer n (%)

Ref.	Country	Subject	Follow-up (yr)	Synchronous cancers	Metachronous cancers
Arima et al[30], 1999	Japan	76	7	5 (6.6)	6 (7.9)
Nasu et al[31], 2005	Japan	143	13.1 (median 4.8)	16 (11.2)	20 (14.0)
Nakajima et al[32], 2006	Japan	633	13.9 (mean 4.4)	58 (9.2)	53 (8.2)
Kobayashi et al[33], 2010	Japan	234	19.6 (median 5.0)	45 (19.2)	30 (12.8)
Han et al[34], 2011	South Korea	176	4	7 (4.0)	9 (5.1)
Kato et al[18], 2013	Japan	1258	6 (mean 2.2)	110 (8.7)	65 (5.2)
Kim et al[35], 2013	South Korea	602	ND	12 (2.0)	ND
Boda et al[36], 2014	Japan	357	9.5 (median 4.4)	50 (14.0)	39 (10.9)
Kosaka et al[37], 2014	Japan	438	9.8	45 (10.2)	34 (7.8)

Number of subjects without eradication. ND: Not described; Synchronous cancers: Second gastric cancers discovered within 1 yr after the initial endoscopic resection; Metachronous cancers: Second gastric cancers discovered 1 yr or later from the initial endoscopic resection.