Equol inhibits proliferation of human gastric carcinoma cells via modulating Akt pathway

Figure 5 Effect of equol on Akt phosphorylation. A: Cells were treated with 20 μmol/L of equol for 12, 24 and 48 h; B: Cells were treated with various concentrations of equol for 24 h. The levels of phosphorylated Akt (Thr450, Thr308 and Ser473) and total Akt were detected by Western blot. GAPDH was utilized as a loading control (^aP < 0.05 vs control; ^bP < 0.01 vs control).