Equol inhibits proliferation of human gastric carcinoma cells via modulating Akt pathway

Figure 1 Effect of equol on the proliferation of MGC-803 cells. A: Cells were treated with various concentrations of equol for 24, 36 and 48 h, and cell viability was determined via MTS assay. The viability of the control group was arbitrarily set at 100%; B: Ki67 mRNA expression after 20 μmol/L of equol treatment for desired time; C: Immunofluorescent detection of Ki67 level (magnification × 200). Cells were stimulated with desired doses of equol for 24 h. Detection of ki67 was conducted as described in “Materials and methods” (^aP < 0.05 vs control, ^bP < 0.01 vs control).