Recql5 protects against lipopolysaccharide/D-galactosamine-induced liver injury in mice

Figure 3 Enhanced inflammatory responses in Recql5-deficient mice following lipopolysaccharide/D-Gal exposure. TNF-α (A) and IL-6 (B) mRNA expression in WT and Recql5-deficient (Recql5^-/-) mice 1 and 6 h after LPS/D-Gal exposure (n = 4-7 per group). Serum TNF-α (C) and IL-6 (D) levels in WT and Recql5-deficient mice 1 and 6 h after LPS/D-Gal administration; E: Hepatic MPO activity in WT and Recql5-deficient mice following LPS/D-Gal challenge; F: Western blot analysis of ERK1/2, JNK, and p65 expression and phosphorylation in the livers of WT and Recql5-deficient mice after LPS/D-Gal treatment. ^aP < 0.05, WT vs Recql5^-/-.