Laparoscopic vs open abdominoperineal resection in the multimodality management of low rectal cancers

Table 4 Clinicopathological features according to neoadjuvant therapy

	No neoCRT					neoCRT
	LAPR		OAPR		P value	LAPR		OAPR		P value
	Mean, n	SD (%)	Mean, n	SD (%)		Mean, n	SD (%)	Mean, n	SD (%)
Age (yr)	58.41	11.98	57.44	12.86	0.623	56.81	10.64	54.77	10.23	0.483
BMI	23.21	3.00	22.84	2.89	0.431	22.90	3.08	23.37	2.74	0.561
Gender					0.113					0.087
Male	42	52.5%	32	40.0%		13	50.0%	19	73.1%
Female	38	47.5%	48	60.0%		13	50.0%	7	26.9%
ASA score					0.429					0.696
I	42	52.5%	37	46.3%		12	46.2%	15	57.7%
II	38	47.5%	43	53.8%		13	50.0%	10	38.5%
III	0	0.0%	0	0.0%		1	3.8%	1	3.8%
Histology					1.000					1.000
Adenocarcinoma	57	80.3%	56	73.7%		5	50.0%	9	75.0%
Mucinous adenocarcinoma	6	7.5%	6	7.5%		3	11.5%	2	7.7%
Pathological stage					0.884					0.970
pCR	NA		NA			2	7.7%	3	11.5%
I	33	41.3%	33	41.3%		10	38.5%	8	30.8%
II	20	25.0%	20	25.0%		4	15.4%	4	15.4%
III	19	23.8%	19	23.8%		6	23.1%	6	23.1%
IV	8	10.0%	8	10.0%		4	15.4%	5	19.2%
Lymphovascular invasion					0.685					1.000
No	66	82.5%	64	80.0%		25	96.2%	26	100.0%
Yes	14	17.5%	16	20.0%		1	3.8%	0	0.0%
Perineural invasion					0.151					0.701
No	62	77.5%	69	86.3%		23	88.5%	21	80.8%
Yes	18	22.5%	11	13.8%		3	11.5%	5	19.2%
Grade					0.224					0.411
NA	9	11.2%	4			16	61.5%	14	53.8%
III/IV	14	17.5%	20	25.0%		5	19.2%	3	11.5%
I/II	57	71.2%	56	70.0%		5	19.2%	9	34.6%
pT category					0.816					0.196
pT0	0	0.0%	0	0.0%		4	15.4%	4	15.4%
pT1	11	13.8%	5	12.5%		1	3.8%	5	19.2%
pT2	27	33.8%	7	30.0%		13	50.0%	7	26.9%
pT3	42	52.5%	10	57.7%		8	30.8%	10	38.5%
pN category					0.337					0.723
pN0	56	70.0%	53	66.3%		18	69.2%	17	65.4%
pN1	17	21.3%	14	17.5%		6	23.1%	8	30.8%
pN2	7	8.8%	13	16.3%		2	7.7%	1	3.8%
Total retrieved nodes	14.58	6.70	14.11	5.35	0.630	7.65	4.73	9.19	3.59	0.193
Distance (cm)	3.73	1.25	3.55	1.26	0.380	4.33	1.50	3.65	1.35	0.095

LAPR: Laparoscopic abdominoperineal resection; OAPR: Open abdominoperineal resection; BMI: Body mass index; ASA: American Society of Anesthesiologists; pCR: Pathological complete remission; neoCRT: Neoadjuvant chemoradiation.