Broccoli sprout extract induces detoxification-related gene expression and attenuates acute liver injury

Table 3 Significantly enriched Kyoto Encyclopedia of Genes and Genomes pathway found in the differentially expressed genes by broccoli sprout extract (P < 0.05)

	KEGG ID	Pathway	FDR-corrected P value
Up-regulated	rno03010	Ribosome	3.97 × 10-43
	rno00980	Metabolism of xenobiotics by cytochrome P450	0.001186149
	rno00982	Drug metabolism	0.004009591
Down-regulated	rno00071	Fatty acid metabolism	2.42 × 10-17
	rno03320	PPAR signaling pathway	2.42 × 10-12
	rno00280	Valine, leucine and isoleucine degradation	5.75 × 10-8
	rno00620	Pyruvate metabolism	8.79 × 10-7
	rno01040	Biosynthesis of unsaturated fatty acids	8.34 × 10-7
	rno00650	Butanoate metabolism	1.21 × 10-6
	rno00830	Retinol metabolism	5.97 × 10-6
	rno00982	Drug metabolism	7.15 × 10-6
	rno00640	Propanoate metabolism	1.06 × 10-5
	rno00020	Citrate cycle (TCA cycle)	4.94 × 10-5
	rno00120	Primary bile acid biosynthesis	5.63 × 10-5
	rno00140	Steroid hormone biosynthesis	7.09 × 10-4
	rno00561	Glycerolipid metabolism	7.78 × 10-4
	rno00010	Glycolysis/gluconeogenesis	0.003660561
	rno00380	Tryptophan metabolism	0.003952492
	rno00983	Drug metabolism	0.004286518
	rno00500	Starch and sucrose metabolism	0.009275005
	rno00980	Metabolism of xenobiotics by cytochrome P450	0.024561245

FDR: False discovery rate.