Circulating microRNAs and long non-coding RNAs in gastric cancer diagnosis: An update and review

Table 4 Expression levels of circulating lncRNAs in gastric cancer tissues and their target miRNAs

Circulating miRNA	Expression in the circulation	Expression in tissue	Validated targeted miRNAs	Putative targeted miRNAs in GC
H19	Up-regulation	Up-regulation	miR-675, let-7 and miR-200 family	miR-17-5p, miR-18a-5p, miR-18b-5p, miR-19a-3p, miR-20a-5p, miR-20b-5p, miR-106a-5p, miR-106b-5,
LINC00152	Up-regulation	Up-regulation	miR-130b-3p, miR-217	miR-18a-5p, miR-18b-5p, miR-31-5p, miR-139-5p, miR-195-5p, miR-497-5p
FER1L4	Down-regulation	Down-regulation	Null	miR-18a-5p, miR-18b-5p, miR-106a-5p, miR-133b, miR-139-5p, miR-195-5p, miR-497-5p
LSINCT-5	Down-regulation	Up-regulation	Null	Null
CUDR (UCA1)	Down-regulation	Up-regulation	miR-216b, miR-1, miR-143	Null
PTENP1	Down-regulation	Null	miR-17, miR-19b, miR-20a, miR21 and miR-26a	Null

GC: Gastric cancer.