Copyright
©The Author(s) 2015.
World J Gastroenterol. Sep 14, 2015; 21(34): 9853-9862
Published online Sep 14, 2015. doi: 10.3748/wjg.v21.i34.9853
Published online Sep 14, 2015. doi: 10.3748/wjg.v21.i34.9853
MicroRNAs | Diagnosis/prognosis | Up/downregulated in plasma/serum | Plasma/serum | Relevance | Ref. |
miR-12 | Yes/No | Upregulated | Serum | Compared with healthy control | [67] |
miR-122 | Yes/No | Upregulated | Serum | [67] | |
miR-223 | Yes/No | Upregulated | Serum | [67] | |
miR-122 | Yes/No | Upregulated | Serum | Compared with healthy control | [68] |
miR-21 | Yes/No | Upregulated | Plasma | Compared with chronic hepatitis or healthy control | [69] |
miR-143 | Yes/No | Upregulated | Serum | Compared with healthy control | [6] |
miR-215 | Yes/No | Upregulated | Serum | [6] | |
miR-10b | Yes/No | Upregulated | Serum | Compared with CLD or healthy control | [74] |
miR-106b | Yes/No | Upregulated | Serum | [74] | |
miR-181a | Yes/No | Downregulated | Serum | [74] | |
miR-206 | Yes/No | Upregulated | Serum | HBV-related HCC compared with cirrhosis or healthy control | [12] |
miR-141-3p | Yes/No | Upregulated | Serum | [12] | |
miR-433-3p | Yes/No | Upregulated | Serum | [12] | |
miR-1228-5p | Yes/No | Upregulated | Serum | [12] | |
miR-199a-5p | Yes/No | Downregulated | Serum | [12] | |
miR-122-5p | Yes/No | Downregulated | Serum | [12] | |
miR-192-5p | Yes/No | Downregulated | Serum | [12] | |
miR-26a-5p | Yes/No | Downregulated | Serum | [12] | |
miR-122 | Yes/No | Downregulated | Plasma | HBV-related HCC compared with chronic hepatitis B or healthy control | [75] |
miR-192 | Yes/No | Upregulated | Plasma | [75] | |
miR-21 | Yes/No | Upregulated | Plasma | [75] | |
miR-223 | Yes/No | Downregulated | Plasma | [75] | |
miR-26a | Yes/No | Downregulated | Plasma | [75] | |
miR-27a | Yes/No | Downregulated | Plasma | [75] | |
miR-801 | Yes/No | Upregulated | Plasma | [75] | |
miR-16 | Yes/No | Downregulated | Serum | Compared with CLD or healthy control | [78] |
miR-21 | Yes/No | Upregulated | Plasma | Compared with chronic hepatitis or healthy volunteers | [69] |
miR-375d | Yes/No | Downregulated | Serum | Compared with healthy control | [87] |
miR-199a-3p | Yes/No | Downregulated | [87] | ||
miR-30c-5p | Yes/No | Upregulated | Serum | HCV-related HCC compared with healthy control | [15] |
miR-223-3p | Yes/No | Downregulated | Serum | [15] | |
miR-302c-3p | Yes/No | Upregulated | Serum | [15] | |
miR-17-5p | Yes/No | Upregulated | Serum | [15] | |
miR-122 | No/Yes | Upregulated | Serum | Improved overall survival | [4] |
miR-1 | No/Yes | Upregulated | Serum | Improved overall survival | [79] |
miR-221 | No/Yes | Upregulated | Serum | High serum miR-221 levels decreased survival rate | [81] |
- Citation: Zhang YC, Xu Z, Zhang TF, Wang YL. Circulating microRNAs as diagnostic and prognostic tools for hepatocellular carcinoma. World J Gastroenterol 2015; 21(34): 9853-9862
- URL: https://www.wjgnet.com/1007-9327/full/v21/i34/9853.htm
- DOI: https://dx.doi.org/10.3748/wjg.v21.i34.9853