Recent advances in the molecular diagnostics of gastric cancer

doi:10.3748/wjg.v21.i34.9838

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Sep 14, 2015 (publication date) through Jul 5, 2024

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Sep 14, 2015; 21(34): 9838-9852
Published online Sep 14, 2015. doi: 10.3748/wjg.v21.i34.9838

Table 5 Gastric cancer-associated long non cording RNAs

Symbol (location)	Materials	Detection methods	Pt	Survival	Relevant clinical factors	Functional analyses	Interacting molecules	In vivo study	Ref.
Early detection
CUDR (19p13.12)	Circulating	QPCR	106	OS	-	-	-	-	[142]
HOTAIR (12q13.13)	Tissue	QPCR	60	-	Perineural invasion, stage	-	-	-	[144]
Prediction of survival
BLACAT1 (1q32.1)	Tissue	QPCR	85	OS	Size, N, stage	Proliferation, migration, invasion	-	-	[147]
CCAT1 (8q24.21)	Tissue	QPCR	62	-	Size, stage	Proliferation, apoptosis	ERK/MAPK pathway	-	[140]
GAPLINC (18)	Tissue	Microarray	90	OS	Size, N	Proliferation, migration	CD44	-	[145]
HIF1A-AS2 (14q23.2)	Tissue	QPCR	83	OS	Depth, N, stage	Proliferation	-	Yes	[146]

Pt: Number of patients enrolled in expression analysis; QPCR: Quantitative real-time reverse transcription-polymerase chain reaction; OS: Overall survival; N: Lymph node metastasis.

Citation: Kanda M, Kodera Y. Recent advances in the molecular diagnostics of gastric cancer. World J Gastroenterol 2015; 21(34): 9838-9852
URL: https://www.wjgnet.com/1007-9327/full/v21/i34/9838.htm
DOI: https://dx.doi.org/10.3748/wjg.v21.i34.9838