CTLA-4 and MDR1 polymorphisms increase the risk for ulcerative colitis: A meta-analysis

Table 2 Comparisons of genotype and allele frequencies between the case and the control groups

SNP	rs3087243 G/A			rs231775 G/A			rs1045642 C/T
	OR	95%CI	P value	OR	95%CI	P value	OR	95%CI	P value
Allele model
Asians	1.15	0.86-1.55	0.340	1.51	1.15-1.98	0.003	1.47	1.19-1.82	< 0.001
Caucasians	1.56	1.06-2.31	0.026	1.72	1.24-2.39	0.001	1.34	1.13-1.59	0.001
Africas	-	-	-	1.56	0.97-2.49	0.066	-	-	-
Overall	1.37	1.02-1.82	0.035	1.58	1.31-1.92	< 0.001	1.39	1.21-1.59	< 0.001
Dominant model
Asians	1.38	0.96-1.97	0.079	1.90	1.31-2.75	0.001	1.72	1.26-2.36	0.001
Caucasians	1.69	1.29-2.19	< 0.001	1.89	1.21-2.95	0.005	1.35	1.00-1.83	0.048
Africas	-	-	-	1.43	0.76-2.68	0.263	-	-	-
Overall	1.57	1.27-1.94	< 0.001	1.81	1.39-2.34	< 0.001	1.52	1.22-1.89	< 0.001
Homozygous model
Overall	2.41	1.67-3.48	< 0.001	2.21	1.45-3.37	< 0.001	1.92	1.44-2.56	< 0.001
Heterozygous model
Overall	0.62	0.44-0.89	0.008	0.76	0.50-1.15	0.190	0.67	0.53-0.86	0.001
Recessive model
Overall	1.98	1.42-2.76	< 0.001	1.73	1.16-2.57	0.007	1.62	1.29-2.05	< 0.001

OR: Odds ratio.