Cavernous hemangioma of adult pancreas: A case report and literature review

Table 1 Previously reported pancreas hemangiomas in literature

No.	Year	Country	Author	Age (yr)/sex	Site/size (cm)	Preoperative diagnosis	Treatment	Follow up
1	1939	-	Ranstrom	61/F	Head/7	Found at autopsy	-
2	1960	France	Ringoir	-	-	-	Surgery
3	1961	France	Ringoir	71/F	Head/15	-	Retrocolic gastroenterostomy, vagotomy
4	1972	France	Colardyn	42/F	Body tail/-	-	Fat free diet, anticholinergic1
5	1985	France	Mangin	62/F	Head to tail/20	Multicystic heterogenous structure	Laparotomy with observation1
6	1991	Japan	Kobayashi	30/M	Head/20	Cavernous hemangioma suggested on US/MRI	Pancreatoduodenectomy
7	1991	Germany	Dageforde	79/F	Body tail/6		Observation1
8	2003	Taiwan	Chang	70/F	Body tail/4	Heterogenous hypervascular solid mass. Serous/cystic adenoma/adenocarcinoma?	Subtotal pancreatectomy	Healthy at 14 mo
9	2006	Austria	Plank	36/M	Head/3	Hypervascular mass. Nonfunctioning neuroendocrine tumor	Hemangioma suspected during laparotomy, confirmed by intraoperative US. Not resected1
10	2008	China	Xu	-	-	Three cases reported	-
11	2009	United States	Mundinger	45/F	Head/5.5	Hypodensity mass in CT. Benign (duplication cyst, paraganglioma, cystic GIST) cyst	Frozen section: benign cyst. PPPD performed
12	2010	-	Jarboui	60/F	-	-	-
13	2011	Israel	Weidenfeld	73/F	Head/5	Cyst with solid part	Whipple’s procedure
14	2011	Malaysia	Lee	49/F	Neck/5	Non-enhancing septated cyst. Mucious cyst with malignant features	Central partial pancreatectomy and gastrostomy	Symptom free at 6 mo
15	2012	Germany	Kersting	53/M	Head/8	Non-enhancing mass. Adenocarcinoma?	Extirpation of the tumor
16	2013	China	Zhi-hua	23/F	Head/5.4	Non enhancing multilocular cyst with fluid fluid levels	Subtotal pancreatectomy	Healthy, no recurrence at 1 yr
17	2013	United Kingdom	Malik	70/F	Head/8	Giant hemangioma suggested on CT	PPPD	Fine at 6 wk
18	2014	United Kingdom	Williamson	78/F	Head/4	Hemangioma per EUS	Observation1
19	2014	Japan	Naito	40/F	Body tail/10	Multilocular septated cystic mass	Pancreatectomy	No recurrence at 6 yr
20	2015	United States	Mondal	18/F	Head/6	Benign cyst	PPPD	Fine at 6 mo

¹Cases that were preoperatively suspected to be hemangioma and/conservatively managed. PPPD: Pylorus preserving pancreatoduodenectomy.