Thyroid dysfunction in Chinese hepatitis C patients: Prevalence and correlation with TPOAb and CXCL10

Table 3 Baseline characteristics of the thyroid dysfunction vs non-thyroid dysfunction chronic hepatitis C patients

	TDIFN	NTDIFN	P value
Gender (%, male/female)	28.0/72.0	55.3/45.7	0.014
Age (yr)1	43.40 ± 13.60	47.50 ± 14.0	0.183
HCV RNA (log10, IU/mL)2	6.23 (3.54, 7.52)	6.36 (3.0, 7.74)	0.919
ALT (IU/L)2	81.0 (26, 416)	55.0 (10, 527)	0.162
AST (IU/L)2	67.0 (26, 248)	41.5 (16, 264)	0.018
TBIL(μmol/L)2	17.20 (8.9, 36.4)	16.0 (5.0, 150.0)	0.732
DBIL(μmol/L)2	4.57 (0.69, 13.80)	4.5 (0.48, 108)	0.447
ALB (g/L)1	42.30 ± 4.24	42.62 ± 4.15	0.764
TPOAb positivity	24.2%	12.3%	0.047
TGAb positivity	12.0%	7.9%	0.469
CXCL10 level (pg/mL)1	310.0 ± 163.4	495.20 ± 244.2	0.012

¹mean ± SD;

²median (minimum, maximum). TBIL: Total bilirubin; DBIL: Direct bilirubin; ALT: Alanine aminotransferase; AST: Aspartate aminotransferase; ALB: Albumin; TPOAb: Thyroid peroxidase antibody; TGAb: Thyroglobulin antibody.