Carvedilol may attenuate liver cirrhosis by inhibiting angiogenesis through the VEGF-Src-ERK signaling pathway

Figure 7 Role of Src in angiogenic signaling. A: HUVECs were treated with VEGF (50 ng/mL) for 2 h in the presence or absence of different concentrations of PP2. Cell lysates were subjected to SDS-PAGE for Src phosphorylation; B: HUVECs were treated with VEGF (50 ng/mL) for 2 h in the presence or absence of different concentrations of PP2. Cell lysates were processed as indicated in the Materials and Methods (n = 3, ^aP < 0.05 vs control, ^bP < 0.01 vs VEGF alone).