Efficacy of hepatic resection vs transarterial chemoembolization for solitary huge hepatocellular carcinoma

Table 1 Clinicopathologic features of all study participants with solitary huge hepatocellular carcinoma (≥ 10 cm) receiving hepatic resection or transarterial chemoembolization n (%)

Variable	HR (n = 180)	TACE (n = 67)	Standardized difference, %	P-value
Age, yr	46.3 ± 11.9	48.1 ± 12.4	14.2	0.307
M/F	158 (87.8)/22 (12.2)	64 (95.5)/3 (4.5)	37.2	0.073
Tumor size, cm	11.3 ± 2.2	11.9 ± 2.2	26.7	0.059
HBsAg (+)	153 (85)	65 (97.0)	70.1	0.009
Child-Pugh class
A	175	64	8.2	0.790
B	5	3
Cirrhosis	133 (73.9)	57 (85.1)	31.2	0.064
AFP
≥ 400 ng/mL	75 (41.7)	37 (55.2)	27.1	0.057
≤ 400 ng/mL	105 (58.3)	30 (44.8)
Total bilirubin, μmol/L	13.4 ± 5.9	16.1 ± 8.4	37.6	0.004
ALT, U/L	50.7 ± 52.4	63.6 ± 44.5	29.1	0.074
AST, U/L	60.6 ± 40.9	56.0 ± 35.4	13.0	0.418
Prothrombin time, s	12.8 ± 1.4	13.1 ± 2.3	9.7	0.355
Albumin, g/L	39.4 ± 4.6	37.5 ± 6.5	29.0	0.012
Platelet count, 109/L	210.0 ± 77.6	213.4 ± 89.4	3.8	0.771
Vascular invasion	26 (14.4)	6 (9.0)	19.1	0.253

Values with ‘‘±’’ are written as mean ± SD or number (%) of patients. ALT: Alanine aminotransferase; AST: Aspartate aminotransferase; AFP: Alpha-fetoprotein; HR: Hepatic resection; TACE: Transarterial chemoembolization.