MiR-30b suppresses tumor migration and invasion by targeting EIF5A2 in gastric cancer

Figure 1 Expression levels of miR-30b in gastric tissue samples and gastric cell lines. A: MiR-30b expression was determined in 23 pairs of gastric cancer tissues compared with corresponding normal tissues by quantitative RT-PCR. Each sample was analyzed in triplicate and normalized to U6. T: tumor tissues; N: adjacent normal tissues; B: Lower miR-30b expression was observed in gastric cancer cell lines compared to that in GES-1; C: AGS and MGC803 cell proliferation was determined by the CCK-8 assay. Upregulation of miR-30b by transfection with mimic suppressed cell proliferation. Downregulation of miR-30b by transfection with inhibitor promoted cell proliferation. Data are displayed as mean ± SD.