Rare case of adult pancreatic hemangioma and review of the literature

Table 1 Adult pancreatic hemangiomas reported in the literature since 1939

Case	Year	Ref.	Age/sex	Symptoms	Diagnostic imaging	Location	Size, cm	Treatment	IHC positivity
1	1939	Ranström[1]	61/F	Found incidentally at autopsy	N/A	Head	7 × 7	N/A	N/A
2	1961	Ringoir et al[2]	71/F	Hemetemesis, melena	Abdominal plain film, iv cholangiography	Head	15	Retrocolic gastroenterostomy, vagotomy	N/A
3	1972	Colardyn et al[3]	42/M	AP, back pain	Abdominal plain film angiography	Body/tail	N/A	Fat-free diet, anticholinergics	N/A
4	1985	Mangin et al[4]	62/F	Malaise, nausea, thrombocytopenia	US, ERCP, non-contrast CT	Head/body/tail	20 × 7	Laparotomy, observation	N/A
5	1991	Kobayashi et al[5]	30/M	Abdominal distention	US, CT, MRI, angiography	Head	20	PD	N/A
6	1991	Dageförde et al[6]	79/F	AP	US, ERCP, angiography	Body/tail junction	6 × 3	Observation	N/A
7	2003	Chang et al[7]	70/F	EP	CT, angiography	Body/tail junction	4.0 × 3.2	Subtotal P	F8
8	2006	Plank et al[8]	36/M	AP	CT, MRI, intraoperative US	Head	3	Laparotomy	N/A
9	2008	Mundinger et al[9]	45/F	EP radiating to back	CT, MRI	Head	6.2 × 5.3	Pylous-preserving PD	CD31, CD34
10	2011	Weidenfeld et al[10]	73/F	AP radiating to the left back	CT	Uncinate process	5 × 4 × 3	PD	CD31, CD34, F8
11	2011	Lee et al[11]	49/F	Dizziness, palpitation	US, CT, EUS	Neck	5	Central P, pancreatogastrostomy	CD34
12	2013	Lu et al[12]	23/F	Found during health examination	US, CT, MRI	Head	5 × 4 × 3	Subtotal P	N/A
13	2014	Naito et al[13]	40/F	AP	CT, MRI	Body/tail	10	P	N/A
14	2015	Present case	28/F	EP	CT	Body/tail	10 × 8	Subtotal P, splenectomy	N/A

AP: Abdominal pain; EP: Epigastric pain; ERCP; Endoscopic retrograde cholangiopancreatography; EUS: Endoscopic ultrasound; F8: Factor VIII-related antigen; IHC: Immunohistochemistry; MRI: Magnetic resonance imaging; N/A: Not available; P: Pancreatectomy; PD: Pancreaticoduodenectomy; US: Ultrasound.