Liver enzymes, metabolomics and genome-wide association studies: From systems biology to the personalized medicine

Figure 1 Schematic representation of different localizations of ALT1 (GPT1) and ALT2 (GPT2) proteins at the cellular level. Prediction was performed by the open access web resource “COMPARTMENTS” available at http://compartments.jensenlab.org, which predicts protein localization according to information extracted from different databases, including UniProtKB, as well as cellular component ontologies visualized by the Gene Ontology Consortium. The program generates unified confidence scores of the localization evidence; confidence scale is color coded, ranging from light green (1) indicating low confidence, to dark green (5), corresponding to high confidence, with absence of localization evidence depicted in white (0). The evidence score is expressed in %.