Pancreatic mass as an initial manifestation of polyarteritis nodosa: A case report and review of the literature

Figure 2 Histological findings of the pancreas, gallbladder and kidney. A: Pancreatic fibrotic changes adjacent to the bile duct (asterisk) are evident. An obliterated medium-sized artery (arrow) is accompanied by cellular infiltration and destruction of the wall. The bile duct mucosa is intact (hematoxylin-eosin stain; original magnification, × 40); B: The affected small-sized artery in the pancreatic fibrosis is characterized by necrotizing arteritis with subintimal fibrinoid necrosis and inflammatory cell infiltration (hematoxylin-eosin stain; original magnification, × 100); C: The arteries of the gallbladder are also involved: the mucosa is preserved (hematoxylin-eosin stain; original magnification, × 40); D and E: Renal biopsy showed segmental sclerosis and collapse with a fibrocellular crescent (D: Periodic acid-Shiff’s stain, original magnification, × 200) and vasculitis of a small-sized artery (E: Periodic acid-Shiff’s stain, original magnification, × 100 ).