Transient elastography improves detection of liver cirrhosis compared to routine screening tests

Table 3 Sensitivities for detection of liver cirrhosis by different combinations of non-invasive examinations

	All patients (n = 182)
	Sensitivity	Specificity	PPV	NPV	P value1
Liver stiffness ≥ 13 kPa and/or ultrasound cirrhosis	96.1%	50.5%	76.5%	88.5%
Liver stiffness ≥ 13 kPa and/or platelets < 150.000/μL	93.9%	49.1%	75.4%	82.8%	< 0.0001
Ultrasound and/or platelets < 150.000/μL	88.2%	68.0%	82.6%	76.9%	< 0.0001
Ultrasound and/or cutaneous liver signs	87.6%	62.0%	79.7%	74.7%	< 0.0001
Platelets < 150000/μL and/or cutaneous liver signs	79.4%	63.7%	78.5%	65%	< 0.004

¹Sensitivity compared to the combination of liver stiffness and/or ultrasound. NS: Not significant; PPV: Positive predictive value; NPV: Negative predictive value.